Showing posts with label Reparative Therapy. Show all posts
Showing posts with label Reparative Therapy. Show all posts

December 1, 2016

Man Cured of Bladder Cancer with Testosterone Experimental Therapy





 

A man with advanced prostate cancer that didn’t seem to be treated has been “cured” by a new experimental therapy.

The new treatment involved shocking tumours to death using testosterone.

Other very ill men involved in the trial saw astonishing results, with tumours being seen to shrink and the progress of the disease stopping in its tracks.

Overall, most of the people involved in the trial seemed to undergo positive results. Scientists tested that by looking at levels of Prostate Specific Antigen (PSA), a blood marker used to monitor prostate cancer – and found that it fell in most of the 47 people involved in the study.

 
And one individual had so little of the market in his body – and no trace of the disease – that doctors said he appears to be cured after 22 cycles of the treatment.

The trial saw the men complete at least three cycles of what is called bipolar androgen therapy, or BAT. That sees their bodies get flooded with testosterone and then starved of it.

Until now, the male hormone had thought to help spur prostate cancer on. And so scientists have traditionally looked to treat it by cutting off the supply of testosterone.

 
Mouth cancer rates up 68% – and unhealthy lifestyles are to blame
But the new study comes off the back of lab experiments that have seen cancer cells get suppressed or even killed by blasts of the same hormone.

Professor Sam Denmeade, from Johns Hopkins University School of Medicine in Baltimore, US, who led the new study, said: "We think the results are unexpected and exciting.

"We are still in the early stages of figuring out how this works and how to incorporate it into the treatment paradigm for prostate cancer.

"Thus far we have observed dramatic PSA response in a subset of men; PSA levels declined in about 40% of men and in about 30% of men levels fell by more than 50%.

"Some men also have objective responses with a decrease in the size of measurable disease, mostly in lymph nodes. Many of the men have stable disease that has not progressed for more than 12 months.

"I think we may have cured one man whose PSA dropped to zero after three months and has remained so now for 22 cycles. His disease has all disappeared."

Early findings from the on-going Restore study were presented at the EORTC-NCI-AACR symposium on Molecular Targets and Cancer Therapeutics in Munich, Germany.

All the patients had spreading cancer that was resistant to treatment with two of the latest hormone therapy drugs, abiraterone and enzalutamide.

The men received high dose injections of testosterone once every 28 days. At the same time, they were given a drug that stopped testosterone being produced naturally by the testicles.

"Our goal is to shock the cancer cells by exposing them rapidly to very high followed by very low levels of testosterone in the blood," said Prof Denmeade.

Six of the men tested positive for a protein called AR-V7 that may be associated with resistance to enzalutamide.

After BAT treatment, no sign of the protein was seen in the blood of all six. Two of the men had declines in PSA level of 50% or more.

The therapy appears to be well-tolerated by the patients, one man experiencing an increase in pain and another having a problem with urine retention.

Prof Denmeade said it was still not clear how the treatment worked, but it appeared to involve cell signalling and part of the process of cell division. Large doses of testosterone also seemed to cause prostate cancer cells to make breaks in their DNA.

Cancer cells stopped dividing and turned "senescent", meaning they "become like old men who sit around and tell stories but don't make much trouble", said the professor.

He cautioned that the therapy was still highly experimental and only suitable for men not suffering painful symptoms.

"Testosterone treatment can definitely worsen pain in men with prostate cancer who have pain from their disease," he said.

A multi-centre randomised US trial called Transformer is now comparing BAT with enzalutamide in men who have become resistant to abiraterone. It aims to recruit a total of 180 participants.

Prof Denmeade said: "If we find testosterone is superior then we would hope to move on to larger trials. Our problem is this is not a drug that is owned by a pharmaceutical company; it is generic testosterone. So moving forward is going to be difficult due to issues with finding funds to run a bigger trial."

Each year around 47,000 men are diagnosed with prostate cancer in the UK and 11,000 die from the disease.

Dr Matt Hobbs, deputy director of research at the charity Prostate Cancer UK, said: "Drugs that reduce the levels of testosterone (androgen deprivation therapy) are an effective treatment for thousands of men with advanced prostate cancer.

"However, at some point the cancer evolves and those drugs stop working. This research is intriguing because it offers a hint that - somewhat unexpectedly - for some men whose cancers have reached that 'hormone-resistant' stage it may be possible to kill or stop growth of the cancer cells by actually overloading them with testosterone.

"Many exciting new lines of attack against prostate cancer are emerging of which this is one.

“However, this is early stage research and further studies are needed in order to understand exactly how intriguing developments like this work and to test the findings more robustly in large clinical trials."


Press Association

June 2, 2015

Mother Rapes Gay son to Make him Straight


                                                                         

A gay boy was raped by his own mother in a misguided attempt to cure him of homosexuality.
An Indian LBGT organisation has warned that parents are so desperate to have straight children they are encouraging cousins, brothers and even mothers to rape their children.
Gay sex is punishable with up to ten years in prison in India, meaning anxious families feel they have no choice but to carry out the "corrective rapes".
A homosexual girl who was in a relationship with another woman was also raped by her cousin in a bid to cure her.
A string of victims have sought help from the LGBT Collective in Telangana, which reported fifteen cases within the past five years.
But Vyjayanti Mogli who works in the southern Indian organisation's crisis intervention team said there were many more victims who were scared to speak out.
He told the Times of India: "We are sure there are many more cases, but they go unreported,
“We came across such cases not because they reported the rape, but because they sought help to flee their homes."

Indian parents are so desperate to have straight children they are encouraging cousins, brothers and even mothers to rape their children, an LBGT organization has warned

Google
Rape: The attack took place in Telengana
He said many victims wanted to block out memories of being attacked by a loved one so preferred to try and forget and cut off contact with their families rather than report it.
Shockingly, the parents are normally aware of the rape and have handpicked a family member, normally a cousin but also brother, father or mother, for the task.
Mr Mogli said in some communities in South India, marriages amongst cousins are common and parents decide which relation their daughter will be married to soon after her birth.
If this girl is discovered to be in a relationship with another girl, "elders in the family believe having sex with the 'would-be', even if it's forcibly, will cure her", he added.
The case of the teenage boy raped by his own mother was one of the many "shocking real life instances" from Bangalore that Hyderabadi filmmaker Deepthi Tadanki is dramatising in his upcoming film, Satyavati.
He said no one wanted to talk about corrective rape and his attempts he had tried reaching out to NGOs for information, only to be rebuffed.
He said: "Many rapes go unreported in India, and it will take years before something like corrective rape even gets talked about. That's why I wanted to tell this story."
In 2013 the Indian Supreme Court reinstated a colonial law which banned gay sex.
RUTH HALKON
Meanwhile a mother in California has been arrested after she made sex tapes with her 16-year-old son.
According to a 'Daily Mail' report, Mistie Rebecca Atkinson, 32, said the relationship was not one of incest, rather a 'genetic attraction'. Mom and son were reunited after 15 years. She's been sentenced to four years and eight months in prison.
The incident came to light after the teen recorded his mother giving him oral sex on his phone. The boy was living with his dad and she had no custody rights. She first contacted him last year via Facebook and started sending inappropriate messages.
She allegedly also sent nude pictures of herself to the teenager.

April 9, 2015

US President Says “Stop Talk About Conversion Therapy of LGBT Youth”


                                                                       
                                                                        
US President Barack Obama has condemned psychiatric therapies designed to "repair" gay, lesbian and transgender youth.
Mr Obama's statement was in response to an online petition calling for a ban on conversion therapies, which gained over 120,000 signatures in three months.
The petition was inspired by Leelah Alcorn, a 17-year-old transgender youth who committed suicide in December.
Some conservative groups and religious doctors support conversion therapy.
"We share your concern about its potentially devastating effects on the lives of transgender as well as gay, lesbian, bisexual, and queer youth," White House adviser Valerie Jarrett wrote in response to the petition. 
"As part of our dedication to protecting America's youth, this administration supports efforts to ban the use of conversion therapy for minors." 
Vigils were held after Ms Alcorn committed suicide in December
Vigils were held after Ms Alcorn committed suicide in December
Counselling and prayer is used in conversion therapy to help some Christians deal with gay urges.
But mental health groups and gay rights activists say it can increase the risk of depression or suicide.
The US states of California and New Jersey have banned the practices. But other conservative states such as Oklahoma are considering legislation to protect the therapies from legal challenges.
While the White House is not explicitly calling for congressional legislation to ban the therapies nationwide, Mara Keisling, the executive director of the National Center for Transgender Equality, welcomed Mr Obama's statement.
"Having President Obama and the weight of the White House behind efforts to ban conversion therapy is so critical in the fight for transgender and LGBT young people," Ms Keisling said.
In the letter posted on Tumblr, Ms Alcorn said she killed herself after years of struggling with her strict Christian parents' refusal to acknowledge her true identity as a female.
She ended her note with a plea: "The only way I will rest in peace is if one day transgender people aren't treated the way I was... My death needs to mean something. Fix society. Please.”

August 1, 2014

Ex Gay Cure Therapy Four - Say Sorry

                                                           

Former members of organizations that advocated therapy to “cure" homosexuality have joined LGBT groups in rejecting the concept. 

But in 2010 she began to see things differently. At the time, Schneider did not share her feelings with her colleagues, but that same year, she was let go from her position as the director of the women’s ministry at Exodus International— a leading sexual orientation conversion organization that closed in 2013.
“I realized that no one was actually saying, ‘I’m straight,” she explains, referring to the post-treatment disposition of the Exodus clients she saw. “You can go through years of therapy and what are you left with—shame?”
Schneider, now 48, realized that simply leaving the movement wasn’t enough. On Monday, she officially apologized for her involvement in the anti-gay movement in an open letter published by GLAAD. And on Thursday she joined with eight other former leaders in the ex-gay movement to formally come out against the controversial practice in an open letter and support a widespread ban of the practice on minors.
“We know first-hand the terrible emotional and spiritual damage it can cause, especially for LGBT youth,” reads the letter, published by the National Center for Lesbian Rights. “We once believed that there was something morally wrong and psychologically ‘broken’ about being LGBT. We know better now.”
The former gay conversion leaders, including Schneider, Brad Allen, Darlene Bogle, Michael Bussee, Catherine Chapman, Jeremy Marks, Bill Prickett, Tim Rymel, and John Smid, are joining the National Center for Lesbian Rights’ #BornPerfect movement aimed at expanding state bans on conversion therapy.
“Conversion therapy reinforces internalized homophobia, anxiety, guilt and depression. It leads to self-loathing and emotional and psychological harm when change doesn’t happen,” the letter reads. “We now stand united in our conviction that conversion therapy is not “therapy,” but is instead both ineffective and harmful.
Currently, California and New Jersey are the only two states that have laws in place to ban the practice of using therapy to try to “cure” minors of homosexuality, though a Michigan lawmaker introduced a bill last week that would ban the practice on minors. In fact, the Texas Republican Partyformally endorsed gay conversion treatments in their official platform in June. Yet, the American Medical Association, the American Psychological Association and most leading professional medical and social science organizations oppose the therapy given its basis in the idea that homosexuality is “curable.”
“The idea that homosexuality is a mental disorder or that the emergence of same-sex attraction and orientation among some adolescents is in anyway abnormal or unhealthy has no support among any mainstream health and mental health professional organizations,” reads an American Psychological Association brochure titled “Just the Facts about Sexual Orientation and Youth.”
Michael Bussee, co-founder of Exodus International who has been speaking out against conversion therapy since 1989, says Thursday’s letter was the next step for leaders in the movement after Exodus closed. Now, he says their efforts should be focused on educating the public and ending the practice.
“There will be people who will be understandably upset, leaders can’t undo the harm they caused while they’re a part of these programs,” says Bussee who in 2007 publicly apologized for his work in the movement from 1976 until 1979. “All we can do know is say this harm needs to stop.”  

June 21, 2014

Chef John Paulk Came Out Gay-after straight Therapy he was straight poster boy-He Comes Out Gay again!


 Poor man, the only gay I know that had to come out twice…..                                                                          

"I may have the genetic coding that I'm inclined to be an alcoholic, but I have the desire not to do that, and I look at the homosexual issue the same way." – Texas Gov. Rick Perry
***

There was a time in my life when I used to sound a lot like Rick Perry. In fact, for more than ten years I was one of the nation’s leading spokesmen for the “ex-gay” movement. I traveled the country telling audiences that being gay was a preventable condition, and it could be treated if only you followed a simple plan, obeyed God and sought repentance for your sins. “Ladies and gentlemen, homosexuality is not a genetic, inborn condition,” I would say. “It is the result of traceable causes that, once unraveled, can bring about understanding and transformation in the life of one who is motivated and submitted to God.”

Oh, I was a believer: Homosexuality was just WRONG. And I was Exhibit A, a self-declared convert who had managed to overcome my own shameful gay past. I even appeared on the cover of Newsweek magazine in 1998, posing alongside my wife as a poster boy for “going straight.” And I was happy to do it: Those stories gave me a national platform to advocate for what is called “gay reparative therapy”—basically, convincing gay people that they were sexually “broken” and could be provided with a way to change. My wife Anne—herself an ex-lesbian—and our three sons were often put forward as evidence of how to accomplish this. Anne and I even wrote a book together preaching the gay-to-straight gospel, Love Won Out: How God’s Love Helped 2 People Leave Homosexuality and Find Each Other.

(Sign up for Politico Magazine's Friday Cover email)
But I was in denial. It wasn’t in fact true, any of it. Worse than being wrong, it was harmful to many people—and caused me years of pain in my own life. Which is why I have this to say to the Rick Perrys of the world: You don’t understand this issue. At all.
Sure, I was gratified to hear that at an event this week, Perry appeared to regret his remarks comparing homosexuality to alcoholism. “I stepped right in it,” he admitted. But this wasn’t just some political mistake. What worries me more is the ignorance betrayed by Perry’s comments—an ignorance that I believe is still widespread among conservatives in the straight world—about what being gay means. The kind of ignorance revealed by those in Perry’s Texas Republican Party who recently inserted a plank in their party platform declaring homosexuality to be a “chosen behavior” and recognizing the “legitimacy and efficacy” of gay reparative therapy.

Paulk and his wife on the cover of Newsweek in 1998.
Luckily, it’s true that across our nation, life is dramatically and rapidly improving for gay people, and it’s encouraging that same-sex marriage has found favor in courts across the land, and is coming to be viewed as legitimate by a majority of Americans, according to polls. But we are not through yet. As long as this widespread misunderstanding in the straight world about homosexuality persists, that it is a choice or a “lifestyle,” as Perry put it, not only will we never be fully accepted by society, some of us will remain unable to accept ourselves. It’s internalized homophobia: you hate what you are. It is a form of self-inflicted torture that has haunted me my entire life, and I do not want young gay women and men today to go through what I went through. I want to tell them—and Rick Perry: We are not broken, damaged, inferior or throwaways. We are created in the image of God—just like everyone else.

***
I had known I was attracted to my own sex since I was 18. I came out as a senior in high school in Ohio and embraced my homosexuality. I found wide acceptance within my family, and I lived openly as a homosexual until the age of 24. But around that point in my life I found myself becoming very despondent, even suicidal. I attributed my unhappiness to my homosexuality. In reality, I was tremendously insecure, lonely and searching for an identity. I could no longer accept myself.
  
The Tragic Success of Freedom Summer
By JOSH ZEITZ
At the time I first began having those doubts, in the mid-1980s, I was attending Ohio State University, where the campus pastor introduced me to Christianity. I told him, “God can’t love me because I’m gay.” The pastor replied, in essence, that this wasn’t true, that God could love me, but he added that if I continued being gay, God would not be pleased with my life. I came to believe that homosexuality was something that God was against, and if I continued to embrace it, I would not be pleasing to Him. And I very much wanted please Him. The pastor found a book in a local Christian bookstore that described a special ministry for gay people in California called Exodus, which was based on the idea that homosexuality could be changed through strong determination and a relationship with Jesus Christ.
I would have crawled to get there. I signed up for a year-long residential program called “Steps Out of Homosexuality.” There were 12 of us in a house, and we ate, worked and did bible study together. We went to church together too. On Tuesday and Thursday nights, we had long discussions about various aspects of homosexuality—including the Exodus view of how it developed from a breakdown in family relationships such as that between a boy and his father. There were plenty of lapses, but we persevered.

by John Paulk  the owner of Mezzaluna, a catering business in Portland, Oregon.


June 9, 2014

Texas GOP Pushes Reparative Therapy for gays

                                                                           


The Texas Republican Party is poised to adopt a new platform this weekend that would support psychological treatments that seek to turn gay people straight. Such therapies were banned for minors last year by New Jersey Republican Gov. Chris Christie, and California has a similar law.
But a fight to remove the therapy language during the Texas GOP convention on Saturday could backfire, said Jeff Davis, chairman of gay conservative group Texas Log Cabin Republicans. A final platform vote would include nearly 10,000 delegates at the biennial convention, which has long been unfriendly territory for gays.
Davis said his group and its allies haven’t settled on a strategy, but that it may be better to adopt a longer-term plan to educate conservatives on the harms of psychological treatments that seek to turn gay people straight.
“Fighting it on the floor may not be the best court of action,” Davis said. “It might be in our best interest to wait until the convention is over and regroup.”
Under the new proposed plank, the Texas GOP would “recognize the legitimacy and efficacy of counseling, which offers reparative therapy and treatment for those patients seeking healing and wholeness from their homosexual lifestyle.”
The American Psychological Association and other major health organizations have condemned such counseling, which generally try to change a person’s sexual orientation or to lessen their interest in engaging in same-sex sexual activity. The groups say the practice should not be used on minors because of the danger of serious psychological harm.
But trying to strip the language from the Texas GOP platform could set off a contentious fight and result in altering the language even more. The therapy phrasing survived a key committee vote late Thursday, but hardliners had sought to change “homosexuality” in the platform to “sexual sins.”
Also on the table is removing decades-old language that states, “homosexuality tears at the fabric of society.” Davis said that was the only language his group sought to change at the convention, and that he still wanted to go home with that win. 
The therapy language was inserted at the urging of Cathie Adams of Dallas, leader of the influential tea party group Texas Eagle Forum and a onetime chairwoman of the Texas Republican Party.
Adams, whose group backed tea party outsiders who dominated Texas Republican primary races this year, said she simply promoted language proposed by a man she said was helped by such therapy, which has been defended by some smaller groups, including the National Association for Research and Therapy of Homosexuality.
“He knows what he’s talking about. He is one of those who has benefited,” Adams said. “I think the majority of Texans feel that way too. It’s not like this is mandatory. This is only a voluntary program.”
In August, New Jersey became the second U.S. state to ban licensed therapists from trying to turn gay teenagers straight. The bill was signed by Christie, a possible 2016 presidential candidate who opposes same-sex marriage but has said he believes people are born gay and that homosexuality isn’t a sin.
Judges on a federal appeals court also upheld a similar ban in California last fall, saying that trying to change a minor’s sexual orientation through intense therapy appeared dangerous. The California Legislature has cited reports, experts and anecdotes involving suicides, substance abuse and other behavior by young recipients of the therapy.
Republican delegate Elizabeth Hunter, 20, said she didn’t see any reason for removing language that describes being gay as tearing at the fabric of society.
“I don’t see anybody leaving the Republican Party because of that language,” she said. “I think it would actually encourage someone to join when they see that the Republican Party takes a strong stand rather than standing in the middle.”
___
Follow Paul J. Weber on Twitter: www.twitter.com/pauljweber

Amazon SearchBox Use it for All Meerchandise

The Forest Needs help

Summer Athlete

Adamfoxie Blog Int.

Adamfoxie Blog Int.
Amazon

ONE

ONE
Relief World Hunger

Taylor Made 2016 Family Clubs

Click Here To Get Anything by Amazon- That will keep US Going

Amazon EcHo

Blog Archive/White No# Stories per Month/year

Popular Posts

Everyday at the Movies

Orangutans ARE Part of the Forest

The Gay Man in You♥ or Him