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Content created by Medical News Today and sponsored by our partners. Learn more What is PrEP (preexposure prophylaxis) for HIV and does it work? Types Who is it for? Effectiveness Access Cost Safety Stopping treatment Vs. PEP On-demand PrEP Summary Preexposure prophylaxis (PrEP) is an HIV prevention treatment that doctors prescribe to people who are HIV-negative but have an increased risk of contracting the virus. PrEP stands for pre-exposure prophylaxis. It is a prophylactic treatment for people who do not have HIV but have an increased risk of contracting it. PrEP contains antiretroviral medications, which lower the risk of acquiring HIV for people exposed to the virus. Antiretroviral medications work by preventing the HIV virus from replicating itself in the body. There are several antiretroviral medications currently approved to prevent HIV. The Food and Drug Administration (FDA) has approved three types of PrEP. This article provides more information about PrEP for HI