Four in 5 Men may Have Symptoms of Testosterone Deficiency, Are You one?
I did not know I needed Testosterone. It just happen that I got an infection or my large intestine and came close to death. Months without eating Im sure will make you imagine how easy it was to loose 100 Lbs in a month, when a guy that weight 180 Lbs. When I recover I was missing a lot of things that food, sun and vitamins does for your body but I was lacking in a hospital bed.. When the Dr. Prescribed Testos for me I questioned it . He showed me the results and said that is was bad. Started using and together with other steroids, and nutrition classes one on one I got my body back.
But testos was kept being prescribed to me. Very forgiving med when you forget but when you need it you better have access to it. I make sure I have plenty because I can tell the difference of when I use it and when I don’t. It will stop your middle age woos. It will make you feel like you can function sexually like you should without shooting any blancs or using the blue pill or any pill that gives you a hard on for 4 hours. Testos is expensive it might not be for everyone. You most consult your physician and see your level. Then shop around for the real stuff and best price.. Not china not mexico or nation that don’t even know what it is. It is available right here in the uSA.
This my story and I hope it helps someone. If you have questions on how it affected me and how it is to use it feel free to ask publicly on the comments section or privately at the reader satisfaction email:
adamfoxie@Outlook.com Adam Gonzalez
Introduction
Four in 5 men may have symptoms of testosterone deficiency, and testosterone replacement can improve body composition and metabolic outcomes related to serum glucose and cholesterol levels. In fact, some research even suggests that testosterone treatment might improve the risk for mortality among men with testosterone deficiency. However, a large new study finds a higher risk for cardiovascular disease or death associated with testosterone therapy, and it is not the first study to do so. The current review provides a balanced perspective regarding the challenging issue of testosterone deficiency and replacement among men.
Background
Testosterone is a complicated and critical hormone that plays multiple roles in vivo. It reduces fat mass and improves insulin sensitivity. [1] Circulating testosterone also helps to reduce serum low-density lipoprotein cholesterol and triglyceride levels. Higher testosterone levels correlate positively with high-density lipoprotein cholesterol levels.
The concentration of free testosterone gradually declines as men age, owing both to decreased production as well as higher concentrations of sex hormone-binding globulin. One longitudinal study of 1156 men found that the mean annual reduction in free testosterone levels was approximately 2%, although this reduction was attenuated among healthier men. [2]
The exact prevalence of testosterone deficiency (TD) is controversial. Many men have symptoms that might indicate TD. In a self-selected study that used a Web-based survey of over 10,000 men, 80% were found to have symptoms consistent with TD. [3] In a study of 2162 men at least 45 years of age who attended primary care clinics in the United States, the prevalence of a total testosterone level less than 300 ng/dL was 38.7%. [4] Less than 10% of these men were receiving testosterone treatment.
Symptoms of TD include fatigue, loss of libido, hot flashes, depression, and sleep disturbance. [5]However, there is not necessarily a linear association between testosterone levels and symptoms. A study in 3413 men failed to determine an association between testosterone levels and overall scores on a psychological health screening tool. [6] Nonetheless, men with TD had worse psychological performance, particularly for anxiety.
TD is associated with obesity and higher rates of insulin resistance, and up to 50% of older men with type 2 diabetes have been found to have TD. [7] Beyond the effect of this association on individual patients, the larger consequences of this association are staggering. In a study that assumed a highly conservative prevalence of TD of 13.4% among middle-aged and older men in the United States, the additional number of cases of diabetes attributable to TD over a 20-year period was 1.1 million. [8] The health consequences of TD were estimated to cost the US economy between $125 and $500 billion over 2 decades.
Lower testosterone levels also appear to promote a higher risk for mortality among men. In a meta-analysis of 12 studies, each decrease of 2.18 in the standard deviation of serum testosterone was associated with a 35% increase in the overall risk for mortality and a 25% increase in risk for cardiovascular mortality. [9] However, the authors of the meta-analysis note that there was significant heterogeneity among studies, and the association between lower serum testosterone levels and mortality was more pronounced among older men. A more recent study finds a U-shaped association between testosterone levels and mortality among men.
Testosterone generally has positive effects on muscle power and fat mass. [11] It also improves bone mineral density while patients are on therapy. However, its effects on mood and quality of life are more mixed; not all randomized trials have supported a therapeutic benefit in this domain. [12] Similarly, although exogenous testosterAlthough there are data to support some of the health benefits of testosterone therapy, the balance of benefit and risk of treatment is far from settled. However, the growth of TD as a disease and treatment target is undeniable.Testosterone therapy also has salutary metabolic effects similar to those of natural circulating testosterone, including reducing insulin resistance and ameliorating the lipid profile. [11] In a placebo-controlled randomized trial that included men with diabetes, testosterone therapy was associated with a mean decrease in glycated hemoglobin levels of 0.45%. [14]
A new study found that the prevalence of testing for testosterone increased dramatically in the United States and United Kingdom between 2000 and 2010. [15] However, it was clear that testing was more targeted in the United Kingdom vs the United States, and the authors suggest that direct-to-consumer advertising in the United States could help explain this difference. Meanwhile, 4%-9% of testosterone therapy prescriptions in the United States appeared to be inappropriate because they were given to men with normal or high testosterone levels.
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